Universitäts-Kinderklinik Würzburg

Pädiatrische Onkologie, Hämatologie und Stammzelltransplantation


Andres O, Wiegering V, König EM, Schneider AL, Semeniak D, Stritt S, Klopocki E, Schulze H (2016): A novel two-nucleotide deletion in HPS6 affects mepacrine uptake and platelet dense granule secretion in a family with Hermansky-Pudlak syndrome. Pediatr Blood Cancer. Epub ahead of print.

Bartelheim K, Nemes K, Seeringer A, Kerl K, Buechner J, Boos J, Graf N, Dürken M, Gerss J, Hasselblatt M, Kortmann RD, Teichert von Luettichau I, Nagel I, Nygaard R, Oyen F, Quiroga E, Schlegel PG, Schmid I, Schneppenheim R, Siebert R, Solano-Paez P, Timmermann B, Warmuth-Metz M, & Frühwald MC (2016): Improved 6-year overall survival in AT/RT – results of the registry study Rhabdoid 2007. Cancer Med. 5(8):1765-75

Braun M, Ress ML, Yoo Y-E, Scholz CJ, Eyrich M, Schlegel PG and Wölfl M (2016): IL 12-mediated sensitizing of T-cell receptor-dependent and –independent tumor cell killing. Oncoimmunology. 5(7):e1188245. doi: 10.1080/2162402X.2016.1188245

Dietl S, Schwinn S, Dietl S, Riedel S, Deinlein F, Rutkowski S, von Bueren AO, Krauss J, Schweitzer T, Vince GH, Picard D, Eyrich M, Rosenwald A, Ramaswamy V, Taylor MD, Remke M, Monoranu CM, Beilhack A, Schlegel PG, Wölfl M (2016): MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties. BMC Cancer. 16:115

Eber S, Andres O (2016): Anämien. Monatsschr Kinderheilkd. 164(1):59-72

Eber S. W., Andres O (2016): Hereditäre Sphärozytose, S1-Leitlinie 025/018. AWMF 12/2016, 1-26

Harris AC, Young R, Devine S, Hogan WJ, Ayuk F, Bunworasate U, Chanswangphuwana C, Efebera YA, Holler E, Litzow M, Ordemann R, Qayed M, Renteria AS, Reshef R, Wölfl M, Chen YB, Goldstein S, Jagasia M, Locatelli F, Mielke S, Porter D, Schechter T, Shekhovtsova Z, Ferrara JL, Levine JE (2016): International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium. Biol Blood Marrow Transplant. 22(1):4-10

Loeffler J, Hafner J, Mengoli C, Wirth C, Heussel CP, Löffler C, White PL, Ullmann AJ, Michel D, Wiegering V, Wölfl M, Schlegel PG, Einsele H, Springer J, Eyrich M (2016): Prospective Biomarker Screening for Diagnosis of Invasive Aspergillosis in High-Risk Pediatric Patients. J Clin Microbiol. 55(1):101-109

Müller I, Altherr D, Eyrich M, Flesch B, Friedmann KS, Ketter R, Oertel J, Schwarz EC, Technau A, Urbschat S, Eichler H (2016): Tumor antigen-specific T cells for immune monitoring of dendritic cell-treated glioblastoma patients. Cytotherapy. 1146-61

Neubauer H, Wölfl M, Ernestus K (2016): Dermatom und Diffusion--Diagnostik und Therapiekontrolle eines undifferenzierten embryonalen Sarkoms der Leber. Rofo. 188(4):389-91

Streng A, Wiegering V, Liese JG (2016): Varicella in pediatric oncology patients in the post-vaccine era-Analysis of routine hospital data from Bavaria (Germany), 2005-2011. Pediatric hematology and oncology. 33(7-8):468-479

van Gool SW, Holm S, Rachor J, Adamson L, Technau A, Maass E, Frühwald MC, Schlegel PG, Eyrich M (2016): Immunotherapy in atypical teratoid-rhabdoid tumors: Data from a survey of the HGG-Immuno Group. Cytotherapy. 18(9):1178-86

von Bueren AO, Kortmann RD, von Hoff K, Friedrich C, Mynarek M, Müller K, Goschzik T, Zur Mühlen A, Gerber N, Warmuth-Metz M, Soerensen N, Deinlein F, Benesch M, Zwiener I, Kwiecien R, Faldum A, Bode U, Fleischhack G, Hovestadt V, Kool M, Jones D, Northcott P, Kuehl J, Pfister S, Pietsch T, Rutkowski S (2016): Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters. J Clin Oncol. 34(34):4151-4160

von Stackelberg A, Locatelli F, Zugmaier G, Handgretinger R, Trippett TM, Rizzari C, Bader P, O'Brien MM, Brethon B, Bhojwani D, Schlegel PG, Borkhardt A, Rheingold SR, Cooper TM, Zwaan CM, Barnette P, Messina C, Michel G, DuBois SG, Hu K, Zhu M, Whitlock JA, Gore L (2016): Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia. J Clin Oncol. 34(36):4381-4389

Weber ML, Schneider DT, Offenmüller S, Kaatsch P, Einsiedel HG, Benesch M, Claviez A, Ebinger M, Kramm C, Kratz C, Lawlor J, Leuschner I, Merkel S, Metzler M, Nustede R, Petsch S, Seeger KH, Schlegel PG, Suttorp M, Zolk O, Brecht IB (2016): Pediatric colorectal carcinoma is associated with excellent outcome in the context of cancer predisposition syndromes. Ped Blood Cancer. 63(4):611-617

Zipfel J, Eyrich M, Schlegel P-G, Wiegering V (2016): Disturbed B cell and DC-Homeostasis in Pediatric cGVHD Patients-Cocultivation Experiments and Review of the Literature. Clin Oncol. 1: 1097

Zlamy M, Almanzar G, Parson W, Schmidt C, Leierer J, Weinberger B, Jeller V, Unsinn K, Eyrich M, Würzner R, Prelog M (2016): Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy. Immun Ageing. 13:3


Andres O, Schulze H, Speer CP (2015): Platelets in neonates: central mediators in haemostasis, antimicrobial defence and inflammation. Thromb Haemost. 113(1):3-12

Chao MM, Ebell W, Bader P, Beier R, Burkhardt B, Feuchtinger T, Handgretinger R, Hanenberg H, Koehl U, Kratz C, Kremens B, Lang P, Meisel R, Mueller I, Roessig C, Sauer M, Schlegel PG, Schulz A, Strahm B, Thol F, Sykora KW (2015): Consensus of German Transplant Centers on Hematopoietic Stem Cell Transplantation in Fanconi Anemia. Klin Padiatr. 227(3):157-165.

Feucht J, Opherk K, Lang P, Kayser S, Hartl L, Bethge W, Matthes-Martin S, Bader P, Albert MH, Maecker-Kolhoff B, Greil J, Einsele H, Schlegel PG, Schuster FR, Kremens B, Rossig C, Gruhn B, Handgretinger R, Feuchtinger T (2015): Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT. Blood. 125(12):1986-94.

Hellwig Y, Yoo YE, Reß ML, Andres O, Braun M, Schlegel PG, Wölfl M (2015): Fulminant skin GvHD with a cytokine pattern resemblant of cytokine release syndrome successfully treated with multimodal immunosuppression including tocilizumab. Pediatr Blood Cancer. 2015 Nov. 62(11):2033-5.

Herbst M, Gazendam R, Reimnitz D, Sawalle-Belohradsky J, Groll A, Schlegel PG, Belohradsky B, Renner E, Klepper J, Grimbacher B, Kuijpers T, Liese J (2015): Chronic Candida albicans Meningitis in a 4-Year-Old Girl with a Homozygous Mutation in the CARD9 Gene (Q295X). Pediatr Infect Dis J. 34(9):999-1002.

Li M, Winkler B, Pabst T, Bley T, Köstler H, Neubauer H (2015): Fast MR Imaging of the Paediatric Abdomen with CAIPIRINHA-Accelerated T1w 3D FLASH and with High-Resolution T2w HASTE: A Study on Image Quality. Gastroenterol Res Pract. 2015:693654

Nowak J, Löbel U, Wölfl M, Schlegel PG, Warmuth-Metz M (2015): MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD). Acta Radiol Open. 4(4):2047981615573655

Ottensmeier H, Zimolong B, Wolff JE, Ehrich J, Galley N, von Hoff K, Kuehl J, Rutkowski S (2015): Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours. Eur J Paediatr Neurol. 19(3):298-307

Pompe RS, von Bueren AO, Mynarek M, von Hoff K, Friedrich C, Kwiecien R, Treulieb W, Lindow C, Deinlein F, Fleischhack G, Kuehl J, Rutkowski S (2015): Intraventricular methotrexate as part of primary therapy for children with infant and/or metastatic medulloblastoma: Feasibility, acute toxicity and evidence for efficacy. Eur J Cancer. 2015;51(17): 2634-42

Sandrock-Lang, K., J. Oldenburg, V. Wiegering, S. Halimeh, S. Santoso, K. Kurnik, L. Fischer, D. A. Tsakiris, M. Sigl-Kraetzig, B. Brand, M. Buhrlen, K. Kraetzer, N. Deeg, M. Hund, E. Busse, A. Kahle and B. Zieger (2015): "Characterisation of patients with Glanzmann thrombasthenia and identification of 17 novel mutations." Thromb Haemost 113: 782.

Schuster FR, Stanglmaier M, Woessmann W, Winkler B, Siepermann M, Meisel R, Schlegel PG, Hess J, Lindhofer H, Borkhardt A, Buhmann R (2015): Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies. Br J Haematol. 169(1): 90-102

Schilbach, K., M. Alkhaled, C. Welker, F. Eckert, G. Blank, H. Ziegler, M. Sterk, F. Müller, K. Sonntag, T. Wieder, H. Braumüller, J. Schmitt, M. Eyrich, S. Schleicher, C. Seitz, A. Erbacher, B.J. Pichler, H. Müller, R. Tighe, A. Lim, S.D. Gillies, W. Strittmatter, M. Röcken (2015): "Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation.“ OncoImmunology 4:7, e1014760.

Schmitt J, Eckardt S, Schlegel PG, Sirén AL, Bruttel VS, Mclaughlin KJ, Wischhusen J, Müller AM (2015): Human parthenogenetic embryonic stem cell-derived neural stem cells express HLA-G and show unique resistance to NK cell-mediated killing. Mol Med. 21:185-96.

Tallen G, Resch A, Calaminus G, Wiener A, Leiss U, Pletschko T, Friedrich C, Langer T, Grabow D, Driever PH, Kortmann RD, Timmermann B, Pietsch T, Warmuth-Metz M, Bison B, Thomale UW, Krauss J, Mynarek M, von Hoff K, Ottensmeier H, Frühwald M, Kramm CM, Temming P, Müller HL, Witt O, Kordes U, Fleischhack G, Gnekow A, Rutkowski S (2015): Strategies to improve the quality of survival for childhood brain tumour survivors. Eur J Paediatr Neurol. 19(6): 619-39

Veys PA, Nanduri V, Baker KS, He W, Bandini G, Biondi A, Dalissier A, Davis JH, Eames GM, Egeler RM, Filipovich AH, Fischer A, Jürgens H, Krance R, Lanino E, Leung WH, Matthes S, Michel G, Orchard PJ, Pieczonka A, Ringdén O, Schlegel PG, Sirvent A, Vettenranta K, Eapen M (2015): Haematopoietic stem cell transplantation for refractory Langerhans cell histiocytosis: outcome by intensity of conditioning. Br J Haematol. 169(5):711-8

von Bueren AO, Friedrich C, von Hoff K, Kwiecien R, Müller K, Pietsch T, Warmuth-Metz M, Hau P, Benesch M, Kuehl J, Kortmann RD, Rutkowski S (2015): Metastatic medulloblastoma in adults: outcome of patients treated according to the HIT2000 protocol. Eur J Cancer. 51(16): 2434-43

Wiegering, A., M. Kunz, M. Hussein, I. Klein, V. Wiegering, F. W. Uthe, U. A. Dietz, C. Jurowich, T. Bley, T. Dandekar, C. T. Germer and C. Ritter (2015): "Diagnostic value of preoperative CT scan to stratify colon cancer for neoadjuvant therapy." Int J Colorectal Dis. 30(8):1067-73.

Wiegering, V. A., I. Klein, C. Wirth, A. Dick, T. Meyer, P. G. Schlegel and A. Wiegering (2015): "Anemia and B Symptoms as Leading Symptoms for a Hepatic Inflammatory Pseudotumor - 2 Case Reports." Klin Padiatr. 227(6-7):363-5.

Winkler, B., J. Aulenbach, T. Meyer, A. Wiegering, M. Eyrich, P. G. Schlegel and V. Wiegering (2015): "Formula-feeding is associated with shift towards Th1 cytokines." Eur J Nutr 54: 129.

Winkler, B., J. Taschik, I. Haubitz, M. Eyrich, P. G. Schlegel and V. Wiegering (2015): "TGFbeta and IL10 have an impact on risk group and prognosis in childhood ALL." Pediatr Blood Cancer 62: 72.

Zils K, Klingebiel T, Behnisch W, Mueller HL, Schlegel PG, Fruehwald M, Suttorp M, Simon T, Werner M, Bielack S (2015): Osteosarcoma in patients with Rothmund-Thomson syndrome. Pediatr Hematol Oncol. 32(1):32-40.


Benesch M, Bartelheim K, Fleischhack G, Gruhn B, Schlegel PG, Witt O, Stachel KD, Hauch H, Urban C, Quehenberger F, Massimino M, Pietsch T, Hasselblatt M, Giangaspero F, Kordes U, Schneppenheim R, Hauser P, Klingebiel T, Frühwald MC (2014): High-dose chemotherapy (HDCT) with auto-SCT in children with atypical teratoid/rhabdoid tumors (AT/RT): a report from the European Rhabdoid Registry (EU-RHAB).
Bone Marrow Transplant. 49(3):370-5.

Braun M, Wölfl M, Wiegering V, Winkler B, Ertan K, Bald R, Schwarz K, Heimpel H, Eyrich M, Schlegel PG (2014): Successful treatment of an infant with CDA type II by intrauterine transfusions and postnatal stem cell transplantation.
Pediatr Blood Cancer 61:743-5

Chandran PA, Keller A, Weinmann L, Seida AA, Braun M, Andreev K, Fischer B, Horn E, Schwinn S, Junker M, Houben R, Dombrowski Y, Dietl J, Finotto S, Wölfl M, Meister G, Wischhusen J. The TGF-β-inducible miR-23a cluster attenuates IFN-γ levels and antigen-specific cytotoxicity in human CD8⁺ T cells.
J Leukoc Biol. 2014 Oct;96(4):633-45.

Eyrich M. Case 19: A one year old boy with SCID. In: Kröger, N, Aversa F (eds): 34 successful treatment reports. Thieme 2014

Eyrich, M., S.C. Schreiber, J. Rachor, J. Krauß , F. Pauwels, J. Hain, M. Wölfl,  M.B. Lutz, S. de Vleeschouwer, P.G. Schlegel, S.W. Van Gool (2014). „Development and validation of a fully GMP-compliant production process of autologous, tumor-lysate pulsed dendritic cells.“ Cytotherapy 16:946.

Fink S, Kunzmann S, Andres O, Eyrich M, Wiegering V (2014): Haemophilia in extreme immature preterm infants: increased risk for intracranial haemorrhage?
J Matern Fetal Neonatal Med 27:621-4

Gerber NU, von Hoff K, Resch A, Ottensmeier H, Kwiecien R, Faldum A, Matuschek C, Hornung D, Bremer M, Benesch M, Pietsch T, Warmuth-Metz M, Kuehl J, Rutkowski S, Kortmann RD (2014): Treatment of children with central nervous system primitive neuroectodermal tumors/pinealoblastomas in the prospective multicentric trial HIT 2000 using hyperfractionated radiation therapy followed by maintenance chemotherapy.
Int J Radiat Oncol Biol Phys. 89(4):863-71

Güngör T, Teira P, Slatter M, Stussi G, Stepensky P, Moshous D, Vermont C, Ahmad I, Shaw PJ, da Cunha JM, Schlegel PG, Hough R, Fasth A, Kentouche K, Gruhn B, Fernandes JF, Lachance S, Bredius R, Resnick IB, Belohradsky BH, Gennery A, Fischer A, Gaspar HB, Schanz U, Seger R, Rentsch K, Veys P, Haddad E, Albert MH, Hassan M; on behalf of the Inborn Errors Working Party of the European Society for Blood and Marrow Transplantation (2014): Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study.
Lancet 383:436-48

Hassold N, Warmuth-Metz M, Winkler B, Kreissl MC, Ernestus K, Beer M, Neubauer H (2014): Hit the mark with diffusion-weighted imaging: metastases of rhabdomyosarcoma to the extraocular eye muscles.
BMC Pediatr.14: 57.

Illhardt T, Ebinger M, Schwarze CP, Feuchtinger T, Furtwängler R, Schlegel PG, Klingebiel T, Greil J, Beck JF, Handgretinger R, Lang P (2014): Children with relapsed or refractory nephroblastoma: favorable long-term survival after high-dose chemotherapy and autologous stem cell transplantation.
Klin Padiatr. 226(6-7):351-6.

Schuster FR, Stanglmaier M, Woessmann W, Winkler B, Siepermann M, Meisel R, Schlegel PG, Hess J, Lindhofer H, Borkhardt A, Buhmann R (2014): Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies. Br J Haematol.
Epub ahead of print.

Streif, W., R. Knofler, W. Eberl, O. Andres, T. Bakchoul, F. Bergmann, K. Beutel, R. Dittmer, S. Gehrisch, S. Gottstein, S. Halimeh, J. Haselbock, W. A. Hassenpflug, S. Heine, S. Holzhauer, S. King, C. M. Kirchmaier, M. Krause, W. Kreuz, W. Losche, R. Mahnel, M. Maurer, A. Nimtz-Talaska, M. Olivieri, H. Rott, M. Schambeck Ch, A. Schedel, F. H. Schilling, M. Schmugge, R. Schneppenheim, U. Scholz, T. Scholz, H. Schulze, A. Siegemund, G. Strauss, K. W. Sykora, C. Wermes, V. Wiegering, I. Wieland, B. Zieger and R. B. Zotz (2014). "[Therapy of inherited diseases of platelet function. Interdisciplinary S2K guideline of the Permanent Paediatric Committee of the Society of Thrombosis and Haemostasis Research (GTH e. V.)]."
Hamostaseologie 34: 269.

Watzka, M., C. Geisen, M. Scheer, R. Wieland, V. Wiegering, T. Dorner, H. J. Laws, F. Gumruk, S. Hanalioglu, S. Unal, D. Albayrak and J. Oldenburg (2014). "Bleeding and non-bleeding phenotypes in patients with GGCX gene mutations."
Thromb Res 134: 856.

Wiegering, A., F. Endter, V. A. Wiegering, C. T. Germer and J. Maroske (2014). "Bowl obstruction due to an incomplete obliterated omphalomesenteric duct." Klin Padiatr 226: 80.

Wiegering, V., J. Frank, S. Freudenberg, H. Morbach, P. G. Schlegel, M. Eyrich and B. Winkler (2014). "Impaired B-cell reconstitution in children after chemotherapy for standard or medium risk acute precursor B-lymphoblastic leukemia."
Leuk Lymphoma 55: 870.

Wiegering V, Schmid S, Andres O, Wirth C, Wiegering A, Meyer T, Winkler B, Schlegel PG, Eyrich M (2014): Thrombosis as a complication of central venous access in pediatric patients with malignancies: a 5-year single-center experience.
BMC Hematol. 14(1):18.

Wölfl M, Greenberg PD. Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells.
Nat Protoc. 2014 Apr;9(4):950-66.

Ziegler S, Skibbe K, Walker A, Ke X, Heinemann FM, Heinold A, Mok JY, van Esch WJ, Yang D, Wölfl M, Timm J. Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells.
J Virol. 2014 Oct;88(19):11080-90.


Andres O, Strehl K, Kölsch U, Kunzmann S, Lebrun AH, Stroh T, Schwarz K, Morbach H, von Bernuth H, Liese J (2013): Even in pneumococcal sepsis CD62L shedding on granulocytes proves to be a reliable functional test for the diagnosis of interleukin-1 receptor-associated kinase-4 deficiency.
Pediatr Infect Dis J 32:1017-9.

Bäuerlein CA, Riedel SS, Baker J, Brede C, Garrote AL, Chopra M, Ritz M, Beilhack GF, Schulz S, Zeiser R, Schlegel PG, Einsele H, Negrin RS, Beilhack A (2013): A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model.
BMC Med 21;11:134.

Beier R, Albert MH, Bader P, Borkhardt A, Creutzig U, Eyrich M, Ehlert K, Gruhn B, Greil J, Handgretinger R, Holter W, Klingebiel T, Kremens B, Lang P, Mauz-Körholz C, Meisel R, Müller I, Peters C, Reinhardt D, Sedlacek P, Schulz A, Schuster FR, Schrauder A, Strahm B, Sykora KW, Wössmann W, Zimmermann M, Sauer MG (2013): Allo-SCT using BU, CY and melphalan for children with AML in second CR.
Bone Marrow Transplant 48:651-6.

Beier R, Schulz A, Hönig M, Eyrich M, Schlegel PG, Holter W, Stachel KD, Ehlert K, Greil J, Nürnberger W, Wössmann W, Bader P, Urban C, Müller I, Suttorp M, Sauer M, Gruhn B, Meisel R, Zimmermann M, Sykora KW (2013): Long-term follow-up of children conditioned with Treosulfan: German and Austrian experience.
Bone Marrow Transplant 48:491-501.

Brehm C, Huenecke S, Pfirrmann V, Rossig C, Mackall CL, Bollard CM, Gottschalk S, Schlegel PG, Klingebiel T, Bader P (2013): Highlights of the third International Conference on Immunotherapy in Pediatric Oncology.
Pediatr Hematol Oncol 30:349-66.

Chapuis AG, Ragnarsson GB, Nguyen HN, Chaney CN, Pufnock JS, Schmitt TM, Duerkopp N, Roberts IM, Pogosov GL, Ho WY, Ochsenreither S, Wölfl M, Bar M, Radich JP, Yee C, Greenberg PD (2013): Transferred WT1-reactive CD8+ T cells can mediate antileukemic activity and persist in post-transplant patients.
Sci Transl Med 5:174ra27.

Dantonello TM, Int-Veen C, Schuck A, Seitz G, Leuschner I, Nathrath M, Schlegel PG, Kontny U, Behnisch W, Veit-Friedrich I, Kube S, Hallmen E, Kazanowska B, Ladenstein R, Paulussen M, Ljungman G, Bielack SS, Klingebiel T, Koscielniak E; Cooperative Weichteilsarkom Studiengruppe (2013): Survival following disease recurrence of primary localized alveolar rhabdomyosarcoma.
Pediatr Blood Cancer 60:1267-73.

Eyrich M, Rachor J, Schreiber SC, Wölfl M, Schlegel PG (2013):
Dendritic cell vaccination in pediatric gliomas: lessons learnt and future perspectives.
Front Pediatr. 10;1:12.

Friedrich C, von Bueren AO, von Hoff K, Gerber NU, Ottensmeier H, Deinlein F, Benesch M, Kwiecien R, Pietsch T, Warmuth-Metz M, Faldum A, Kuehl J, Kortmann RD, Rutkowski S (2013): Treatment of young children with CNS-primitive neuroectodermal tumors/pineoblastomas in the prospective multicenter trial HIT 2000 using different chemotherapy regimens and radiotherapy.
Neuro Oncol 15:224-34.

Friedrich C, von Bueren AO, von Hoff K, Kwiecien R, Pietsch T, Warmuth-Metz M, Hau P, Deinlein F, Kuehl J, Kortmann RD, Rutkowski S (2013): Treatment of adult nonmetastatic medulloblastoma patients according to the paediatric HIT 2000 protocol: a prospective observational multicentre study.
Eur J Cancer 49:893-903.

Hofmann M, Schlegel PG, Hippert F, Schmidt P, von-Schweinitz D, Leuschner I, Göbel U, Calaminus G, Schneider DT; MAKEI study group (2013): Testicular sex cord stromal tumors: analysis of patients from the MAKEI study.
Pediatr Blood Cancer 60:1651-5.

Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott PA, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM (2013); International Cancer Genome Consortium PedBrain Tumor Project (2013):
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
Nat Genet 45:927-32.

Shmukler BE, Mukodzi S, Andres O, Eber S, Alper SL (2013): Autosomal dominant overhydrated stomatocytosis associated with the heterozygous RhAG mutation F65S: a case of missed heterozygosity due to allelic dropout.
Br J Haematol 161:602-4.

Tan SM, Kapp M, Flechsig C, Kapp K, Rachor JE, Eyrich M, Loeffler J, Einsele H, Grigoleit GU (2013): Stimulating surface molecules, Th1-polarizing cytokines, proven trafficking--a new protocol for the generation of clinical-grade dendritic cells.
Cytotherapy 15:492-506.

Wiegering V, Andres O, Schlegel PG, Deinlein F, Eyrich M, Sturm A (2013): Hyperfibrinolysis and acquired factor XIII deficiency in newly diagnosed pediatric malignancies.
Haematologica 98:e90-1.

Wiegering V, Schlegel PG, Winkler B (2013): Immune function in newly diagnosed children with malignancy.
J Pediatr Hematol Oncol 34:559-64.

Wiegering V, Sauer K, Winkler B, Eyrich M, Schlegel PG (2013): Indication for allogeneic stem cell transplantation in Glanzmann's thrombasthenia.
Hamostaseologie 33:305-12.

Wiegering V, Winkler B, Haubitz I, Wölfl M, Schlegel PG, Eyrich M (2013): Lower TGFß serum levels and higher frequency of IFNγ-producing T cells during early immune reconstitution in surviving children after allogeneic stem cell transplantation.
Pediatr Blood Cancer 60:121-8.

Winkler B, Kuhn S, Kunzmann S, Ruf K, Wiegering V, Schlegel PG (2013): Severe Hypertriglyceridemia in a 6 Year Old Boy with ALL Relapse: Successfully Treated with Plasmapheresis.Klin Padiatr 225:364-365.

Wölfl M, Langhammer F, Wiegering V, Eyrich M, Schlegel PG (2013): Dasatinib medication causing profound immunosuppression in a patient after haploidentical SCT: functional assays from whole blood as diagnostic clues.
Bone Marrow Transplant 48:875-7.

Wölfl M, Schwinn S, Yoo YE, Reß ML, Braun M, Chopra M, Schreiber SC, Ayala VI, Ohlen C, Eyrich M, Beilhack A, Schlegel PG (2013): Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis.
Blood 122:1203-13.


Corbacioglu S, Cesaro S, Faraci M, Valteau-Couanet D, Gruhn B, Rovelli A, Boelens JJ, Hewitt A, Schrum J, Schulz AS, Müller I, Stein J, Wynn R, Greil J, Sykora KW, Matthes-Martin S, Führer M, O'Meara A, Toporski J, Sedlacek P, Schlegel PG, Ehlert K, Fasth A, Winiarski J, Arvidson J, Mauz-Körholz C, Ozsahin H, Schrauder A, Bader P, Massaro J, D'Agostino R, Hoyle M, Iacobelli M, Debatin KM, Peters C, Dini G (2012):  Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haematopoietic stem-cell transplantation : an open-label, phase 3, randomised controlled trial.
Lancet 1301-1309

Gerber NU, von Hoff K, von Bueren AO, Treulieb W, Deinlein F, Benesch M, Zwiener I, Soerensen N, Warmuth-Metz M, Pietsch T, Mittler U, Kuehl J, Kortmann RD, Grotzer MA, Rutkowski S (2012): A long duration of the prediagnostic symptomatic interval is not associated with an unfavourable prognosis in childhood medulloblastoma.
Eur J Cancer 48:2028-36

Kapp M, Grigoleit GU, Dietz UA, Wiegering V, Stuhler G, Schlegel N, Einsele H, Mielke S, Germer CT, Strauss A (2012): Prevention of major infectious complications by pre-emptive enterostomy in patients awaiting allogeneic stem cell transplantation.
Int J Colorectal Dis 27:1683-1685

Kronik N, Kogan Y, Schlegel PG, Wölfl M (2012): Improving T cell immunotherapy for melanoma through a mathematically motivated strategy: efficacy in numbers?
J of Immunotherapy 35:116-124

Neubauer H, Evangelista L, Hassold N, Winkler B, Schlegel PG, Köstler H, Hahn D, Beer M (2012): Diffusion-weighted MRI for detection and differentiation of musculoskeletal tumor-like lesions in pediatric patients.
World J Pediatr 8 (4): 342-49.

Ronceray L, Pötschger U, Janka G, Gadner H, Minkov M; German Society for Pediatric Hematology and Oncology, Langerhans Cell Histiocytosis Study Group (2012): Pulmonary involvement in pediatric-onset multisystem Langerhans cell histiocytosis: effect on course and outcome.
J Pediatr. 161(1):129-33.e1-3.

Sandrock K, Halimeh S, Wiegering V, Kappert G, Sauer K, Deeg N, Busse E. Zieger B (2012): Homozygous point mutations in platelet glycoprotein ITGA2B gene as cause of Glanzmann thrombasthenia in 2 families.
Klin Pädiatr 224:174-178

Slee RB, Steiner CM, Herbert BS, Vance GH, Hickey RJ, Schwarz T, Christan S, Radovich M, Schneider BP, Schindelhauer D, Grimes BR (2012): Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability.
Oncogene. 31:3244-53

Styczynski J, Balduzzi A, Gil L, Labopin M, Hamladji RM, Marktel S, Yesilipek MA, Fagioli F, Ehlert K, Matulova M, Dalle JH, Wachowiak J, Miano M, Messina C, Diaz MA, Vermylen C, Eyrich M, Badell I, Dreger P, Gozdzik J, Hutt D, Rascon J, Dini G, Peters C (2012): Risk of complications during hematopoietic stem cell collection in pediatric sibling donors: a prospective EBMT-PDWP study.
Blood 119:2935-42

Thiel U, Wolf P, Wawer A, Blaeschke F, Grunewald TG, von Lüttichau IT, Klingebiel T, Bader P, Borkhardt A, Laws HJ, Handgretinger R, Lang P, Schlegel PG, Eyrich M, Gruhn B, Ehninger G, Koscielniak E, Klein C, Sykora KW, Holler E, Mauz-Körholz C, Woessmann W, Richter GH, Schmidt AH, Peters C, Dirksen U, Jürgens H, Bregni M, Burdach  (2012)S. Human leukocyte antigen distribution in German Caucasians with advanced Ewing’s sarcoma.
Klin Pädiatr  224:353-358.

Wiegering V, Schlegel PG, Winkler B (2012): Immune function in newly diagnosed children with malignancy.
J Pediatr Hematol Oncol, 34:559-564

Wolff B, Ng A, Roth D, Parthey K, Warmuth-Metz M, Eyrich M, Kordes U, Kortmann R, Pietsch T, Kramm C, Wolff JE (2012): Pediatric high grade glioma of the spinal cord: results of the HIT-GBM database.
J Neurooncol 107:139-46


Eyrich M, Schreiber SC, Wollny G, Ziegler H, Schlenker R, Koch-Buttner K, Wolfl M, Schlegel PG, Schilbach K (2011): Pre-differentiated human committed T-lymphoid progenitors promote peripheral T-cell re-constitution after stem cell transplantation in immunodeficient mice. Eur J Immunol 41:3596-3603

Gerber NU, von Hoff K, von Bueren AO, Treulieb W, Warmuth-Metz M, Pietsch T, Soerensen N, Faldum A, Emser A, Schlegel PG, Deinlein F, Kortmann RD, Rutkowski S (2011): Outcome of 11 children with ependymoblastoma treated within the prospective HIT-trials between 1991 and 2006. J Neurooncol 102:459-469

Kreyenberg H, Jarisch A, Bayer C, Schuster B, Willasch A, Strahm B, Kremens B, Gruhn B, Schrauder A, Burdach S, Fuhrer M, Rossig C, Kabisch H, Schlegel PG, Stachel D, Beck JF, Mauz-Koerholz C, Chung TL, Holler E, Klingebiel T, Bader P (2011): NOD2/CARD15 gene polymorphisms affect outcome in pediatric allogeneic stem cell transplantation.

Lang P, Pfeiffer M, Teltschik HM, Schlegel P, Feuchtinger T, Ebinger M, Klingebiel T, Bader P, Schlegel PG, Beck J, Greil J, Handgretinger R (2011): Natural killer cell activity influences outcome after T cell depleted stem cell transplantation from matched unrelated and haploidentical donors. Best Pract Res Clin Haematol 24:403-411

Pufnock JS, Cigal M, Rolczynski LS, Andersen-Nissen E, Wolfl M, McElrath MJ, Greenberg PD (2011): Priming CD8+ T cells with dendritic cells matured using TLR4 and TLR7/8 ligands together enhances generation of CD8+ T cells retaining CD28. Blood 117: 6542-6551

Rettinger E, Willasch AM, Kreyenberg H, Borkhardt A, Holter W, Kremens B, Strahm B, Woessmann W, Mauz-Koerholz C, Gruhn B, Burdach S, Albert MH, Schlegel PG, Klingebiel T, Bader P (2011): Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation.
Blood 118:5681-5688

Schlegel P, Teltschik HM, Pfeiffer M, Handgretinger R, Schumm M, Koscielniak E, Feuchtinger T, Klingebiel T, Bader P, Schlegel PG, Greil J, Lang P (2011): Long-term IL-2 therapy after transplantation of T cell depleted stem cells from alternative donors in children.
Best Pract Res Clin Haematol 24:443-452

Thiel U, Wawer A, Wolf P, Badoglio M, Santucci A, Klingebiel T, Basu O, Borkhardt A, Laws HJ, Kodera Y, Yoshimi A, Peters C, Ladenstein R, Pession A, Prete A, Urban EC, Schwinger W, Bordigoni P, Salmon A, Diaz MA, Afanasyev B, Lisukov I, Morozova E, Toren A, Bielorai B, Korsakas J, Fagioli F, Caselli D, Ehninger G, Gruhn B, Dirksen U, Abdel-Rahman F, Aglietta M, Mastrodicasa E, Torrent M, Corradini P, Demeocq F, Dini G, Dreger P, Eyrich M, Gozdzik J, Guilhot F, Holler E, Koscielniak E, Messina C, Nachbaur D, Sabbatini R, Oldani E, Ottinger H, Ozsahin H, Schots R, Siena S, Stein J, Sufliarska S, Unal A, Ussowicz M, Schneider P, Woessmann W, Jurgens H, Bregni M, Burdach S (2011): No improvement of survival with reduced- versus high-intensity conditioning for allogeneic stem cell transplants in Ewing tumor patients.
Ann Oncol 22:1614-1621

von Bueren AO, von Hoff K, Pietsch T, Gerber NU, Warmuth-Metz M, Deinlein F, Zwiener I, Faldum A, Fleischhack G, Benesch M, Krauss J, Kuehl J, Kortmann RD, Rutkowski S (2011): Treatment of young children with localized medulloblastoma by chemotherapy alone: results of the prospective, multicenter trial HIT 2000 confirming the prognostic impact of histology. Neuro Oncol 13:669-679

von Bueren AO, Warmuth-Metz M, Schlegel PG, Soerensen N, Krauss J, Roggendorf W, Pietsch T, Feiden W, Graf N, Pohl F, Flentje M, Kuehl J, Rutkowski S (2011): Late complete remission of supratentorial primitive neuroectodermal tumor (CNS-PNET) after multiple relapses. Pediatr Blood Cancer 56:503-505

von Hoff K, Hinkes B, Dannenmann-Stern E, von Bueren AO, Warmuth-Metz M, Soerensen N, Emser A, Zwiener I, Schlegel PG, Kuehl J, Fruhwald MC, Kortmann RD, Pietsch T, Rutkowski S (2011): Frequency, risk-factors and survival of children with atypical teratoid rhabdoid tumors (AT/RT) of the CNS diagnosed between 1988 and 2004, and registered to the German HIT database.
Pediatr Blood Cancer 57:978-985

Wiegering V, Eyrich M, Rutkowski S, Wolfl M, Schlegel PG, Winkler B (2011): TH1 predominance is associated with improved survival in pediatric medulloblastoma patients.
Cancer Immunol Immunother 60:693-703

Wiegering V, Schick J, Beer M, Weissbrich B, Gattenlohner S, Girschick HJ, Liese J, Schlegel PG, Eyrich M (2011): Varicella-zoster virus infections in immunocompromised patients - a single centre 6-years analysis. BMC Pediatr 11:31

Wiegering V, Winkler B, Langhammer F, Wolfl M, Wirbelauer J, Sauer K, Kobsar A, Meyer T, Strauss A, Bakchoul T, Eyrich M, Schlegel PG (2011): Allogeneic hematopoietic stem cell transplantation in Glanzmann thrombasthenia complicated by platelet alloimmunization.
Klin Padiatr 223:173-175

Wölfl M, Merker K, Morbach H, Van Gool SW, Eyrich M, Greenberg PD, Schlegel PG (2011): Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapy.
Cancer Immunol Immunother 60:173-186


Benesch M, Weber-Mzell D, Gerber NU, von Hoff K, Deinlein F, Krauss J, Warmuth-Metz M, Kortmann RD, Pietsch T, Driever PH, Quehenberger F, Urban C, Rutkowski S (2010): Ependymoma of the spinal cord in children and adolescents: a retrospective series from the HIT database.
J Neurosurg Pediatr 6: 137-144

Coosemans A, Wolfl M, Berneman ZN, Van Tendeloo V, Vergote I, Amant F, Van Gool SW (2010): Immunological response after therapeutic vaccination with WT1 mRNA-loaded dendritic cells in end-stage endometrial carcinoma.
Anticancer Res 30: 3709-3714

Niemeyer CM, Kang MW, Shin DH, Furlan I, Erlacher M, Bunin NJ, Bunda S, Finklestein JZ, Sakamoto KM, Gorr TA, Mehta P, Schmid I, Kropshofer G, Corbacioglu S, Lang PJ, Klein C, Schlegel PG, Heinzmann A, Schneider M, Stary J, van den Heuvel-Eibrink MM, Hasle H, Locatelli F, Sakai D, Archambeault S, Chen L, Russell RC, Sybingco SS, Ohh M, Braun BS, Flotho C, Loh ML (2010): Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia.
Nat Genet 42: 794-800

Rutkowski S, von Hoff K, Emser A, Zwiener I, Pietsch T, Figarella-Branger D, Giangaspero F, Ellison DW, Garre ML, Biassoni V, Grundy RG, Finlay JL, Dhall G, Raquin MA, Grill J (2010): Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis.
J Clin Oncol 28: 4961-4968

Schlegel PG, Eyrich M, Kramm C, van Gool S (2010): Tumor vaccination for high-grade glioma.
Pediatr Blood Cancer 55: 1437

von Hoff K, Hartmann W, von Bueren AO, Gerber NU, Grotzer MA, Pietsch T, Rutkowski S (2010): Large cell/anaplastic medulloblastoma: outcome according to myc status, histopathological, and clinical risk factors.
Pediatr Blood Cancer 54: 369-376

Wolff JE, Driever PH, Erdlenbruch B, Kortmann RD, Rutkowski S, Pietsch T, Parker C, Metz MW, Gnekow A, Kramm CM (2011): Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol.
Cancer 116:705-12

Wolfl M, Merker K, Morbach H, Van Gool SW, Eyrich M, Greenberg PD, Schlegel PG (2011): Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapy.
Cancer Immunol Immunother 60: 173-186


Benesch M, Siegler N, Hoff K, Lassay L, Kropshofer G, Muller H, Sommer C, Rutkowski S, Fleischhack G, Urban C (2009): Safety and toxicity of intrathecal liposomal cytarabine (Depocyte) in children and adolescents with recurrent or refractory brain tumors: a multi-institutional retrospective study.
Anticancer Drugs 20: 794-799

Eyrich M, Wiegering V, Lim A, Schrauder A, Winkler B, Schlegel PG (2009): Immune function in children under chemotherapy for standard risk acute lymphoblastic leukaemia - a prospective study of 20 paediatric patients.
Br J Haematol 147: 360-370

Hacker S, Dittrich A, Mohr A, Schweitzer T, Rutkowski S, Krauss J, Debatin KM, Fulda S (2009): Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.
Oncogene 28: 3097-3110

Herrera L, Bostrom B, Gore L, Sandler E, Lew G, Schlegel PG, Aquino V, Ghetie V, Vitetta ES, Schindler J (2009): A phase 1 study of Combotox in pediatric patients with refractory B-lineage acute lymphoblastic leukemia.
J Pediatr Hematol Oncol 31: 936-941

Kuball J, Hauptrock B, Malina V, Antunes E, Voss RH, Wolfl M, Strong R, Theobald M, Greenberg PD (2009): Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.
J Exp Med 206: 463-475

Menaa F, Houben R, Eyrich M, Broecker EB, Becker JC, Wischhusen J (2009): Stem cells, melanoma and cancer stem cells: the good, the bad and the evil?
G Ital Dermatol Venereol 144: 287-296

Pfister S, Remke M, Benner A, Mendrzyk F, Toedt G, Felsberg J, Wittmann A, Devens F, Gerber NU, Joos S, Kulozik A, Reifenberger G, Rutkowski S, Wiestler OD, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A (2009): Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci.
J Clin Oncol 27: 1627-1636

Rutkowski S, Gerber NU, von Hoff K, Gnekow A, Bode U, Graf N, Berthold F, Henze G, Wolff JE, Warmuth-Metz M, Soerensen N, Emser A, Ottensmeier H, Deinlein F, Schlegel PG, Kortmann RD, Pietsch T, Kuehl J (2009): Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy.
Neuro Oncol 11: 201-210

Schlegel PG, Wolfl M, Schick J, Winkler B, Eyrich M (2009): Transient loss of consciousness in pediatric recipients of dimethylsulfoxide (DMSO)-cryopreserved peripheral blood stem cells independent of morphine co-medication.
Haematologica 94: 1473-1475

Schneider D, Monoranu CM, Huang B, Rutkowski S, Gerber NU, Krauss J, Puppe B, Roggendorf W (2009): Pediatric supratentorial ependymomas show more frequent deletions on chromosome 9 than infratentorial ependymomas: a microsatellite analysis.
Cancer Genet Cytogenet 191: 90-96

Straathof KC, Rao K, Eyrich M, Hale G, Bird P, Berrie E, Brown L, Adams S, Schlegel PG, Goulden N, Gaspar HB, Gennery AR, Landais P, Davies EG, Brenner MK, Veys PA, Amrolia PJ (2009): Haemopoietic stem-cell transplantation with antibody-based minimal-intensity conditioning: a phase 1/2 study.
Lancet 374: 912-920

van Dorp S, Pietersma F, Wolfl M, Verdonck LF, Petersen EJ, Lokhorst HM, Martens E, Theobald M, van Baarle D, Meijer E, Kuball J (2009): Rituximab treatment before reduced-intensity conditioning transplantation associates with a decreased incidence of extensive chronic GVHD.
Biol Blood Marrow Transplant 15: 671-678

von Bueren AO, von Hoff K, Benesch M, Rutkowski S (2009): Dose reductions of vincristine in children with medulloblastoma treated in the maintenance arm of the prospective multicenter trial HIT'91.
Klin Padiatr 221: 396-397

von Hoff K, Hinkes B, Gerber NU, Deinlein F, Mittler U, Urban C, Benesch M, Warmuth-Metz M, Soerensen N, Zwiener I, Goette H, Schlegel PG, Pietsch T, Kortmann RD, Kuehl J, Rutkowski S (2009): Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT'91.
Eur J Cancer 45: 1209-1217

Wachter-Giner T, Bieber I, Warmuth-Metz M, Brocker EB, Hamm H (2009): Multiple pilomatricomas and gliomatosis cerebri--a new association?
Pediatr Dermatol 26: 75-78

Wiegering V, Eyrich M, Wunder C, Gunther H, Schlegel PG, Winkler B (2009): Age-related changes in intracellular cytokine expression in healthy children.
Eur Cytokine Netw 20: 75-80


Beer M, Stenzel M, Girschick H, Schlegel PG, Darge K (2008): [Whole-body MR imaging in children with suspected osteonecrosis after intensive chemotherapy: preliminary results].
Rofo 180: 238-245

De Vleeschouwer S, Fieuws S, Rutkowski S, Van Calenbergh F, Van Loon J, Goffin J, Sciot R, Wilms G, Demaerel P, Warmuth-Metz M, Soerensen N, Wolff JE, Wagner S, Kaempgen E, Van Gool SW (2008): Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme.
Clin Cancer Res 14: 3098-3104

Hasselblatt M, Jozwiak J, Mayer K, Monoranu CM, Schweitzer T, Gerber NU, Krauss J, Schropp C, Bleier S, Kotulska K, Rutkowski S, Pietsch T, Sorensen N, Kersting C, Roggendorf W, Paulus W (2008): Hypothalamic papillary tumor in a patient with tuberous sclerosis.
Am J Surg Pathol 32: 1578-1580

Huang J, Grotzer MA, Watanabe T, Hewer E, Pietsch T, Rutkowski S, Ohgaki H (2008): Mutations in the Nijmegen breakage syndrome gene in medulloblastomas.
Clin Cancer Res 14: 4053-4058

Lang P, Mueller I, Greil J, Bader P, Schumm M, Pfeiffer M, Hoelle W, Klingebiel T, Heinzelmann F, Belka C, Schlegel PG, Kremens B, Woessmann W, Handgretinger R (2008): Retransplantation with stem cells from mismatched related donors after graft rejection in pediatric patients.
Blood Cells Mol Dis 40: 33-39

Monoranu CM, Huang B, Zangen IL, Rutkowski S, Vince GH, Gerber NU, Puppe B, Roggendorf W (2008): Correlation between 6q25.3 deletion status and survival in pediatric intracranial ependymomas.
Cancer Genet Cytogenet 182: 18-26

Reinhard H, Reinert J, Beier R, Furtwangler R, Alkasser M, Rutkowski S, Fruhwald M, Koscielniak E, Leuschner I, Kaatsch P, Graf N (2008): Rhabdoid tumors in children: prognostic factors in 70 patients diagnosed in Germany.
Oncol Rep 19: 819-823

Riethmueller J, Vonthein R, Borth-Bruhns T, Grassme H, Eyrich M, Schilbach K, Stern M, Gulbins E (2008): DNA quantification and fragmentation in sputum after inhalation of recombinant human deoxyribonuclease.
Cell Physiol Biochem 22: 347-352

Rutkowski S, Fleischhack G (2008): Medulloblastome, primitiv neuroektodermale Tumoren und Ependymome.
Monatsschrift Kinderheilkd 156: 1165-1172

Rutkowski S, Fleischhack G, Gnekow A, Kramm C, Müller H, Calaminus G, Wrede B, Frühwald M, Krauss J, Faldum A, Kortmann RD, Pietsch T, Warmuth-Metz M (2008): Hirntumoren bei Kindern und Jugendlichen: Leitsymptome und diagnostische Standards.
Monatsschrift Kinderheilkd 156: 1187-1193

Schilbach K, Frommer K, Meier S, Handgretinger R, Eyrich M (2008): Immune response of human propagated gammadelta-T-cells to neuroblastoma recommend the Vdelta1+ subset for gammadelta-T-cell-based immunotherapy.
J Immunother 31: 896-905

Simon A, Ammann RA, Bode U, Fleischhack G, Wenchel HM, Schwamborn D, Gravou C, Schlegel PG, Rutkowski S, Dannenberg C, Korholz D, Laws HJ, Kramer MH (2008): Healthcare-associated infections in pediatric cancer patients: results of a prospective surveillance study from university hospitals in Germany and Switzerland.
BMC Infect Dis 8: 70

von Hoff K, Kieffer V, Habrand JL, Kalifa C, Dellatolas G, Grill J (2008): Impairment of intellectual functions after surgery and posterior fossa irradiation in children with ependymoma is related to age and neurologic complications.
BMC Cancer 8: 15

Warmuth-Metz M, Bison B, Dannemann-Stern E, Kortmann R, Rutkowski S, Pietsch T (2008): CT and MR imaging in atypical teratoid/rhabdoid tumors of the central nervous system.
Neuroradiology 50: 447-452

Wolff JE, Classen CF, Wagner S, Kortmann RD, Palla SL, Pietsch T, Kühl J, Gnekow A, Kramm CM (2008): Subpopulations of malignant gliomas in pediatric patients: analysis of the HIT-GBM database.
J Neurooncol. 87(2):155-64.

Wolff JE, Kramm C, Kortmann RD, Pietsch T, Rutkowski S, Jorch N, Gnekow A, Driever PH (2008): Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma.
J Neurooncol 90: 309-314

Wolfl M, Kuball J, Eyrich M, Schlegel PG, Greenberg PD (2008): Use of CD137 to study the full repertoire of CD8+ T cells without the need to know epitope specificities.
Cytometry A 73: 1043-1049


Eyrich M, Winkler B, Schlegel PG (2007): Stem cell transplantation in Fanconi anemia - recent advances with alternate donors. IN. Schindler D, Hoehn H (eds): Fanconi Anemia. A Paradigmatic Disease for the Understanding of Cancer and Aging. Monogr Hum Genet 15: 173-182

Grotzer MA, von Hoff K, von Bueren AO, Shalaby T, Hartmann W, Warmuth-Metz M, Emser A, Kortmann RD, Kuehl J, Pietsch T, Rutkowski S (2007): Which clinical and biological tumor markers proved predictive in the prospective multicenter trial HIT'91--implications for investigating childhood medulloblastoma.
Klin Padiatr 219: 312-317

Hinkes BG, von Hoff K, Deinlein F, Warmuth-Metz M, Soerensen N, Timmermann B, Mittler U, Urban C, Bode U, Pietsch T, Schlegel PG, Kortmann RD, Kuehl J, Rutkowski S (2007): Childhood pineoblastoma: experiences from the prospective multicenter trials HIT-SKK87, HIT-SKK92 and HIT91.
J Neurooncol 81: 217-223

Kuball J, Dossett ML, Wolfl M, Ho WY, Voss RH, Fowler C, Greenberg PD (2007): Facilitating matched pairing and expression of TCR chains introduced into human T cells.
Blood 109: 2331-2338

Lukashova-v Zangen I, Kneitz S, Monoranu CM, Rutkowski S, Hinkes B, Vince GH, Huang B, Roggendorf W (2007): Ependymoma gene expression profiles associated with histological subtype, proliferation, and patient survival.
Acta Neuropathol 113: 325-337

Pfister S, Remke M, Toedt G, Werft W, Benner A, Mendrzyk F, Wittmann A, Devens F, von Hoff K, Rutkowski S, Kulozik A, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A (2007): Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas.
Genes Chromosomes Cancer 46: 839-851

Rutkowski S (2007): How can we optimize the timely referral of children with suspected CNS malignancies?
Lancet Oncol 8: 664

Rutkowski S, von Bueren A, von Hoff K, Hartmann W, Shalaby T, Deinlein F, Warmuth-Metz M, Soerensen N, Emser A, Bode U, Mittler U, Urban C, Benesch M, Kortmann RD, Schlegel PG, Kuehl J, Pietsch T, Grotzer M (2007): Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91.
Clin Cancer Res 13: 2651-2657

Schilbach K, Schick J, Wehrmann M, Wollny G, Simon P, Schlegel PG, Eyrich M (2007): PD-1-PD-L1 pathway is involved in suppressing alloreactivity of heart infiltrating t cells during murine gvhd across minor histocompatibility antigen barriers.
Transplantation 84: 214-222

Wolfl M, Kuball J, Ho WY, Nguyen H, Manley TJ, Bleakley M, Greenberg PD (2007): Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities.
Blood 110: 201-210


Abele-Horn M, Vogel U, Klare I, Konstabel C, Trabold R, Kurihara R, Witte W, Kreth W, Schlegel PG, Claus H (2006): Molecular epidemiology of hospital-acquired vancomycin-resistant enterococci.
J Clin Microbiol 44: 4009-4013

Ho WY, Nguyen HN, Wolfl M, Kuball J, Greenberg PD (2006): In vitro methods for generating CD8+ T-cell clones for immunotherapy from the naive repertoire.
J Immunol Methods 310: 40-52

Kramm CM, Wagner S, Van Gool S, Schmid H, Strater R, Gnekow A, Rutkowski S, Wolff JE (2006): Improved survival after gross total resection of malignant gliomas in pediatric patients from the HIT-GBM studies.
Anticancer Res 26: 3773-3779

Rutkowski S (2006): Current treatment approaches to early childhood medulloblastoma.
Expert Rev Neurother 6: 1211-1221

Timmermann B, Kortmann RD, Kühl J, Rutkowski S, Meisner C, Pietsch T, Deinlein F, Urban C, Warmuth-Metz M, Bamberg M (2006): Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials.
J Clin Oncol. 24(10):1554-60.

Wolff JE, Wagner S, Reinert C, Gnekow A, Kortmann RD, Kühl J, Van Gool SW (2006): Maintenance treatment with interferon-gamma and low-dose cyclophosphamide for pediatric high-grade glioma.
J Neurooncol. 79(3):315-21.

Wagner S, Benesch M, Berthold F, Gnekow AK, Rutkowski S, Strater R, Warmuth-Metz M, Kortmann RD, Pietsch T, Wolff JE (2006): Secondary dissemination in children with high-grade malignant gliomas and diffuse intrinsic pontine gliomas.
Br J Cancer 95: 991-997

Wagner S, Warmuth-Metz M, Emser A, Gnekow AK, Strater R, Rutkowski S, Jorch N, Schmid HJ, Berthold F, Graf N, Kortmann RD, Pietsch T, Sorensen N, Peters O, Wolff JE (2006): Treatment options in childhood pontine gliomas.
J Neurooncol 79: 281-287


Eyrich M, Burger G, Marquardt K, Budach W, Schilbach K, Niethammer D, Schlegel PG (2005): Sequential expression of adhesion and costimulatory molecules in graft-versus-host disease target organs after murine bone marrow transplantation across minor histocompatibility antigen barriers.
Biol Blood Marrow Transplant 11: 371-382

Eyrich M, Wollny G, Tzaribaschev N, Dietz K, Brugger D, Bader P, Lang P, Schilbach K, Winkler B, Niethammer D, Schlegel PG (2005): Onset of thymic recovery and plateau of thymic output are differentially regulated after stem cell transplantation in children.
Biol Blood Marrow Transplant 11: 194-205

Feuchtinger T, Richard C, Pfeiffer M, Neuhauser F, Lucke J, Handgretinger R, Greil J, Bader P, Klingebiel T, Schlegel PG, Jahn G, Niethammer D, Lang P (2005): Adenoviral infections after transplantation of positive selected stem cells from haploidentical donors in children: an update.
Klin Padiatr 217: 339-344

Kerst G, Kreyenberg H, Roth C, Well C, Dietz K, Coustan-Smith E, Campana D, Koscielniak E, Niemeyer C, Schlegel PG, Muller I, Niethammer D, Bader P (2005): Concurrent detection of minimal residual disease (MRD) in childhood acute lymphoblastic leukaemia by flow cytometry and real-time PCR.
Br J Haematol 128: 774-782

Klingebiel T, Lang P, Schumm M, Koehl U, Bader P, Schwabe D, Schlegel PG, Eyrich M, Greil J, Beck JF, Niethammer D, Handgretinger R (2005): Experiences with haploidentical stem cell transplantation in children with acute lymphoblastic leukemia.
Pathol Biol (Paris) 53: 159-161

Lang P, Schumm M, Greil J, Bader P, Klingebiel T, Muller I, Feuchtinger T, Pfeiffer M, Schlegel PG, Niethammer D, Handgretinger R (2005): A comparison between three graft manipulation methods for haploidentical stem cell transplantation in pediatric patients: preliminary results of a pilot study.
Klin Padiatr 217: 334-338

Rutkowski S, Bode U, Deinlein F, Ottensmeier H, Warmuth-Metz M, Soerensen N, Graf N, Emser A, Pietsch T, Wolff JE, Kortmann RD, Kuehl J (2005): Treatment of early childhood medulloblastoma by postoperative chemotherapy alone.
N Engl J Med 352: 978-986

Schilbach K, Kerst G, Walter S, Eyrich M, Wernet D, Handgretinger R, Xie W, Rammensee HG, Muller I, Buhring HJ, Niethammer D (2005): Cytotoxic minor histocompatibility antigen HA-1-specific CD8+ effector memory T cells: artificial APCs pave the way for clinical application by potent primary in vitro induction.
Blood 106: 144-149

Timmermann B, Kortmann RD, Kühl J, Rutkowski S, Dieckmann K, Meisner C, Bamberg M (2005): Role of radiotherapy in anaplastic ependymoma in children under age of 3 years: results of the prospective German brain tumor trials HIT-SKK 87 and 92.
Radiother Oncol. 77(3):278-85.

Wolfl M, Jungbluth AA, Garrido F, Cabrera T, Meyen-Southard S, Spitz R, Ernestus K, Berthold F (2005): Expression of MHC class I, MHC class II, and cancer germline antigens in neuroblastoma.
Cancer Immunol Immunother 54: 400-406


De Vleeschouwer S, Van Calenbergh F, Demaerel P, Flamen P, Rutkowski S, Kaempgen E, Wolff JE, Plets C, Sciot R, Van Gool SW (2004): Transient local response and persistent tumor control in a child with recurrent malignant glioma: treatment with combination therapy including dendritic cell therapy. Case report.
J Neurosurg 100: 492-497

Eyrich M, Leiler C, Croner T, Lang P, Schumm M, Mascher B, Schilbach K, Klingebiel T, Handgretinger R, Niethammer D, Schlegel PG (2004): Impaired T-cell activation and cytokine productivity after transplantation of positively selected CD34+ allogeneic hematopoietic stem cells.
Hematol J 5: 329-340

Frühwald MC, Rickert CH, O'Dorisio MS, Madsen M, Warmuth-Metz M, Khanna G, Paulus W, Kühl J, Jürgens H, Schneider P, Müller HL (2004): Somatostatin receptor subtype 2 is expressed by supratentorial primitive neuroectodermal tumors of childhood and can be targeted for somatostatin receptor imaging.
Clin Cancer Res. 10(9):2997-3006.

Kortmann RD, Timmermann B, Rutkowski S, Bamberg M (2004): Re: B. Beuthien-Baumann, et al. Differentiation between recurrent tumor and radiation necrosis in a child with anaplastic ependymoma after chemotherapy and radiation therapy. Strahlenther Onkol 2003;179:819-22.
Strahlenther Onkol 180: 245

Kühl J, Rutkowski S, Schlegel PG (2004): Hirntumoren. In: Speer/Gahr (Hrsg): Pädiatrie, 2. Auflage, Kapitel 28 Hirntumoren (Springer-Verlag, Heidelberg)
Lang P, Greil J, Bader P, Handgretinger R, Klingebiel T, Schumm M, Schlegel PG, Feuchtinger T, Pfeiffer M, Scheel-Walter H, Fuhrer M, Martin D, Niethammer D (2004): Long-term outcome after haploidentical stem cell transplantation in children.
Blood Cells Mol Dis 33: 281-287

Lang P, Klingebiel T, Bader P, Greil J, Schumm M, Schlegel PG, Eyrich M, Mueller-Weihrich S, Niethammer D, Handgretinger R (2004): Transplantation of highly purified peripheral-blood CD34+ progenitor cells from related and unrelated donors in children with nonmalignant diseases.
Bone Marrow Transplant 33: 25-32

Lehrnbecher T, Fleischhack G, Hanisch M, Deinlein F, Simon A, Bernig T, Chanock SJ, Klingebiel T (2004): Circulating levels and promoter polymorphisms of interleukins-6 and 8 in pediatric cancer patients with fever and neutropenia.
Haematologica. 89(2):234-6.

Rutkowski S (2004): HIT 2000. Multizentrische Therapie-Optimierungsstudie zur Behandlung von Kindern und jungen Erwachsenen mit einem intrakranial lokalisierten primitiv neuroektodermalen Tumor (PNET/Medulloblastom) und Ependymom.
Forum Deutsche Krebsgesellschaft 4: 61-63

Rutkowski S, De Vleeschouwer S, Kaempgen E, Wolff JE, Kuhl J, Demaerel P, Warmuth-Metz M, Flamen P, Van Calenbergh F, Plets C, Sorensen N, Opitz A, Van Gool SW (2004): Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study.
Br J Cancer 91: 1656-1662

Rutkowski S, Gnekow A, Wolff J (2004): Multimodale Therapiekonzepte für Kinder und Jugendliche mit Hirntumoren.
Journal Onkologie 08: 25-29

Schilbach K, Schick J, Fluhr H, Marquordt K, Wehrmann M, Schutt BS, Schlegel PG, Niethammer D, Eyrich M (2004): Organ-specific T cell receptor repertoire in target organs of murine graft-versus-host after transplantation across minor histocompatibility antigen barriers.
Transplantation 78: 31-40

Wagner S, Erdlenbruch B, Längler A, Gnekow A, Kühl J, Albani M, Völpel S, Bucsky P, Emser A, Peters O, Wolff JE (2004): Oral topotecan in children with recurrent or progressive high-grade glioma: a Phase I/II study by the German Society for Pediatric Oncology and Hematology.
Cancer. 100(8):1750-7.

Warmuth-Metz M, Kühl J, Krauss J, Solymosi L (2004): Subdural enhancement on postoperative spinal MRI after resection of posterior cranial fossa tumours.
Neuroradiology. 46(3):219-23.

Wolff JEA, Rutkowski S, Kortmann RD (2004): Hirntumoren im Kindesalter. In: Schmoll/Höffken/Possinger (Hrsg): Kompendium Internistische Onkologie, 4. Auflage. Kapitel 153. Hirntumoren im Kindesalter (Springer-Verlag, Heidelberg)
Wolfl M, Schalk S, Hellmich M, Huster KM, Busch DH, Berthold F (2004): Quantitation of MHC tetramer-positive cells from whole blood: evaluation of a single-platform, six-parameter flow cytometric method.
Cytometry A 57: 120-130


Bürger B, Zimmermann M, Mann G, Kühl J, Löning L, Riehm H, Reiter A, Schrappe M (2003): Diagnostic cerebrospinal fluid examination in children with acute lymphoblastic leukemia: significance of low leukocyte counts with blasts or traumatic lumbar puncture.
J Clin Oncol. 21(2):184-8.

Eyrich M, Leiler C, Lang P, Schilbach K, Schumm M, Bader P, Greil J, Klingebiel T, Handgretinger R, Niethammer D, Schlegel PG (2003): A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors.
Bone Marrow Transplant 32: 379-390

Kuci S, Wessels JT, Buhring HJ, Schilbach K, Schumm M, Seitz G, Loffler J, Bader P, Schlegel PG, Niethammer D, Handgretinger R (2003): Identification of a novel class of human adherent CD34- stem cells that give rise to SCID-repopulating cells.
Blood 101: 869-876

Lang P, Handgretinger R, Niethammer D, Schlegel PG, Schumm M, Greil J, Bader P, Engel C, Scheel-Walter H, Eyrich M, Klingebiel T (2003): Transplantation of highly purified CD34+ progenitor cells from unrelated donors in pediatric leukemia.
Blood 101: 1630-1636

Lehrnbecher T, Deinlein F, Marx A, Kuhl J (2003): Mediastinal T-cell lymphoma in a boy 7 years after treatment of supratentorial primitive neuroectodermal tumor.
J Pediatr Hematol Oncol 25: 657-659

Lehrnbecher T, Trusen A, Deinlein F, Hocht B, Marx A, Kuhl J (2003): B-Cell lymphoproliferative disorder not associated with Epstein-Barr Virus in a child with relapsed acute lymphoblastic leukemia.
Med Pediatr Oncol 40: 13-17

Ljungman P, Ribaud P, Eyrich M, Matthes-Martin S, Einsele H, Bleakley M, Machaczka M, Bierings M, Bosi A, Gratecos N, Cordonnier C (2003): Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: a survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation.
Bone Marrow Transplant 31: 481-486

Tomaske M, Bosk A, Eyrich M, Bader P, Niethammer D (2003): Risks of mortality in children admitted to the paediatric intensive care unit after haematopoietic stem cell transplantation.
Br J Haematol 121: 886-891

Warmuth-Metz M, Kühl J, Rutkowski S, Krauss J, Solymosi L (2003): Differential infratentorial brain tumor diagnosis in children.
Radiologe. 43(11):977-85.


Eyrich M, Croner T, Leiler C, Lang P, Bader P, Klingebiel T, Niethammer D, Schlegel PG (2002): Distinct contributions of CD4(+) and CD8(+) naive and memory T-cell subsets to overall T-cell-receptor repertoire complexity following transplantation of T-cell-depleted CD34-selected hematopoietic progenitor cells from unrelated donors.
Blood 100: 1915-1918

Huang B, Starostik P, Kuhl J, Tonn JC, Roggendorf W (2002): Loss of heterozygosity on chromosome 22 in human ependymomas.
Acta Neuropathol 103: 415-420

Langer T, Martus P, Ottensmeier H, Hertzberg H, Beck JD, Meier W (2002): CNS late-effects after ALL therapy in childhood. Part III: neuropsychological performance in long-term survivors of childhood ALL: impairments of concentration, attention, and memory.
Med Pediatr Oncol. 38(5):320-8.

Lehrnbecher T, Stanescu A, Kuhl J (2002): Short courses of intravenous empirical antibiotic treatment in selected febrile neutropenic children with cancer.
Infection 30: 17-21

Muller HL, Marx A, Trusen M, Schneider P, Kuhl J (2002): Disseminated malignant ectomesenchymoma (MEM): case report and review of the literature.
Pediatr Hematol Oncol 19: 9-17

Timmermann B, Kortmann RD, Kuhl J, Meisner C, Dieckmann K, Pietsch T, Bamberg M (2002): Role of radiotherapy in the treatment of supratentorial primitive neuroectodermal tumors in childhood: results of the prospective German brain tumor trials HIT 88/89 and 91.
J Clin Oncol 20: 842-849

Timmermann B, Kortmann RD, Kuhl J, Willich N, Bamberg M (2002): [Interdisciplinary therapy of childhood ependymomas].
Strahlenther Onkol 178: 469-479

Warmuth-Metz M, Kuhl J (2002): [Neuroradiological differential diagnosis in medulloblastomas and ependymomas: results of the HIT'91-study].
Klin Padiatr 214: 162-166

Wolff JE, Gnekow AK, Kortmann RD, Pietsch T, Urban C, Graf N, Kuhl J (2002): Preradiation chemotherapy for pediatric patients with high-grade glioma.
Cancer 94: 264-271

Wolff JE, Wagner S, Sindichakis M, Pietsch T, Gnekow A, Kortmann RD, Strater R, Kuehl J (2002): Simultaneous radiochemotherapy in pediatric patients with high-grade glioma: a phase I study.
Anticancer Res 22: 3569-3572

Wolff JE, Westphal S, Molenkamp G, Gnekow A, Warmuth-Metz M, Rating D, Kuehl J (2002): Treatment of paediatric pontine glioma with oral trophosphamide and etoposide.
Br J Cancer 87: 945-949


Creutzig U, Ritter J, Zimmermann M, Hermann J, Gadner H, Sawatzki DB, Niemeyer CM, Schwabe D, Selle B, Boos J, Kuhl J, Feldges A (2001): Idarubicin improves blast cell clearance during induction therapy in children with AML: results of study AML-BFM 93. AML-BFM Study Group.
Leukemia 15: 348-354

Eyrich M, Lang P, Lal S, Bader P, Handgretinger R, Klingebiel T, Niethammer D, Schlegel PG (2001): A prospective analysis of the pattern of immune reconstitution in a paediatric cohort following transplantation of positively selected human leucocyte antigen-disparate haematopoietic stem cells from parental donors.
Br J Haematol 114: 422-432

Girschick HJ, Klein R, Scheurlen WG, Kuhl J (2001): Cytogenetic and histopathologic studies of congenital supratentorial primitive neuroectodermal tumors: a case report.
Pathol Oncol Res 7: 67-71

Handgretinger R, Klingebiel T, Lang P, Schumm M, Neu S, Geiselhart A, Bader P, Schlegel PG, Greil J, Stachel D, Herzog RJ, Niethammer D (2001): Megadose transplantation of purified peripheral blood CD34(+) progenitor cells from HLA-mismatched parental donors in children.
Bone Marrow Transplant 27: 777-783

Vince GH, Herbold C, Klein R, Kuhl J, Pietsch T, Franz S, Roosen K, Tonn JC (2001): Medulloblastoma displays distinct regional matrix metalloprotease expression.
J Neurooncol 53: 99-106


Bader P, Stoll K, Huber S, Geiselhart A, Handgretinger R, Niemeyer C, Einsele H, Schlegel PG, Niethammer D, Beck J, Klingebiel T (2000): Characterization of lineage-specific chimaerism in patients with acute leukaemia and myelodysplastic syndrome after allogeneic stem cell transplantation before and after relapse.
Br J Haematol 108: 761-768

Chen Y, Zeng D, Schlegel PG, Fidler J, Chao NJ (2000): PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific tolerance in bone marrow transplantation in mice.
Blood 95: 705-710

Haber HP, Schlegel PG, Dette S, Ruck P, Klingebiel T, Niethammer D (2000): Intestinal acute graft-versus-host disease: findings on sonography.
AJR Am J Roentgenol 174: 118-120

Kortmann RD, Kuhl J, Timmermann B, Mittler U, Urban C, Budach V, Richter E, Willich N, Flentje M, Berthold F, Slavc I, Wolff J, Meisner C, Wiestler O, Sorensen N, Warmuth-Metz M, Bamberg M (2000): Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT '91.
Int J Radiat Oncol Biol Phys 46: 269-279

Lal S, Lauer UM, Niethammer D, Beck JF, Schlegel PG (2000): Suicide genes: past, present and future perspectives.
Immunol Today 21: 48-54

Reinhardt D, Behnke-Mursch J, Weiss E, Christen HJ, Kuhl J, Lakomek M, Pekrun A (2000): Rhabdoid tumors of the central nervous system.
Childs Nerv Syst 16: 228-234

Schlegel PG, Eyrich M, Bader P, Handgretinger R, Lang P, Niethammer D, Klingebiel T (2000): OKT-3-based reconditioning regimen for early graft failure in HLA-non-identical stem cell transplants.
Br J Haematol 111: 668-673

Seidemann K, Henze G, Beck JD, Sauerbrey A, Kuhl J, Mann G, Reiter A (2000): Non-Hodgkin's lymphoma in pediatric patients with chromosomal breakage syndromes (AT and NBS): experience from the BFM trials.
Ann Oncol 11 Suppl 1: 141-145